So Many Biomarkers, So Little Time

Unlocking Cytokine Detection: Pre-Conjugated Antibody Pairs for Critical Research

Detecting cytokines at ultra-low levels is essential for understanding immune response, inflammation, and disease progression. However, for many researchers, the reliable detection of low-abundance targets, such as IL-4, IL-6, and TNF-α, remains challenging with standard methods.

Cavidi’s new pre-conjugated antibody pair kits change that equation. Optimized for our BOLD-enabled Exazym® platform, these kits deliver ultrasensitive detection without specialized equipment or workflow changes, while dramatically simplifying assay development.

IL-6: The Inflammation Sentinel IL-6 serves as a critical biomarker in COVID-19, sepsis, and autoimmune diseases. Yet standard ELISA methods often struggle with clinically relevant concentrations. Our IL-6 Antibody Pair Kit delivers high sensitivity and reproducibility, making it easier to track subtle immune responses in infection models, drug trials, and patient samples where every picogram matters.

Read our white paper for performance data.

IL-4: Unlocking Allergy and Immunotherapy Research IL-4 drives Th2-mediated immune responses and serves as a key biomarker in asthma, allergy, and immunotherapy research. We recently demonstrated 50X sensitivity improvement using our IL-4 pair with Exazym, pushing detection well into the femtogram-per-milliliter range. This breakthrough opens new possibilities for studying early allergic responses and therapeutic interventions.

See the full workflow in our webinar and application note.

TNF-α: Precision for Autoimmunity and Oncology TNF-α regulates inflammation, autoimmune pathology, and tumor microenvironment dynamics—making it indispensable for therapeutic monitoring and disease progression studies. Our TNF-α Antibody Pair Kit enables ultra-low-level detection critical for capturing transient or low-grade inflammatory responses that standard assays miss.

Read our application note for complete performance data.

Why Pre-Conjugated Matters 

Time is precious in research. Our pre-conjugated pairs eliminate days of optimization work and reduce variability—they’re ready to run with Exazym® for ultrasensitive detection with minimal startup time.

Whether you’re validating therapeutic targets, tracking disease progression, or pushing assay performance limits, these kits offer a fast, reliable, scalable solution.

The Bottom Line: Don’t let sensitivity constraints limit your cytokine research. These three kits represent the most critical inflammatory markers across infectious disease, allergy, and autoimmunity research—with the ultrasensitivity BOLD delivers.

Let Exazym® do the heavy lifting—so you can focus on the science.  Explore all three kits and integration guides at www.cavidi.se

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